I am all for having options. I have driven with the trailer all thru the mountains of the north east and they are beautiful in the summer, but I would never consider doing it in the winter. I77/I95 is probably your best alternative if you want to make decent time and the drive thru WV is amazing. However, there are not as many stops for gas and food, and fewer campgrounds especially in WV. The grades are a lot steeper and longer in WV and you will be mountain driving almost as soon as you cross into PA from NY almost to Charlotte NC, that is almost half of the drive. All you need is one bad stretch of snow and you could loose 4 hours due to traffic, have to stay over in a Walmart for an extra day waiting for the weather to pass or end up down the side of a mountain.
The I75 route only has about 2 hours of mountain driving in between Lexington and Knoxville. It feels like I75 has an exit with food and gas every 15 minutes. Just my 2 cents...
