I lived 2 years in Myrtle Beach about 50 years ago. It didn't but could get below freezing. Most of November-February it was too cold for the heat pump and we had to run resistance heating as emergency heat. Weather was mostly gray, and when wet, just cold rain but sometimes freezing rain. If the roads iced up, everything stopped until the weather warmed up.
Most of my work took me inland 50-100 miles, where it was often below freezing. Overcoat or lined trenchcoat over coat and tie was adequate for trips from car to a building. More time outdoors, I wore my Michigan winter gear.
My duties took me into three counties in N.C. They weren't much different from the six I worked in NE S.C., coastal and coastal plain.
N.C. has a lot more variation, actual coast, coastal plain, piedmont, Appalachian mountains have quite different climates. The mountains can get serious winter weather, though the worst of that is on the Tennessee side.
I'm from Michigan, would consider snowbirding there sticks and bricks (because I still like at least a little winter weather) but not in a RV which might be marginally insulated for the cold spells. If I didn't want to deal with winter weather, I'd be somewhere south of Savannah, and to stay above freezing most of the time, Fort Myers or beyond.
My daughter lived a couple years at Fayetteville, on the N.C. coastal plain, and it could get really cold. But she could drive to Wilmington, where temperatures were moderated by an ocean too big to freeze.