My 2 cents, based on many years of RV travel. There seem to be three limitations on tires and their ability to carry a load. Of course these are changed by the user and how we use them.
Each rim has a designed ability to carry weight and hold pressure. They should be stamped into the rim somewhere. If not, contact your RV manufacturer, if they are those that came with the RV (if they are still in business) and they will have that information. If they are after-market wheels contact the wheel manufacturer. As all of us should know, never exceed either rating.
Each tire has a different load rating that is affected by inflation. Each tire manufacturer publishes a tire inflation guide that is available on-line.
Now weigh your truck/trailer combo in fully loaded trim, as if you are on a trip, then fit the inflation into the tables. Remember how many tires you have on the trailer and divide the weight by the number of tires. That is how much load each tire will have to carry.
So, the three variables are; the wheel and its designed limitations on weight and maximum pressure, the individual tire and its construction/weight ratings at different pressures, and the load to be carried.
We should also always be aware of the limitations of age, wear and tear, and deterioration on wheels. They won't last forever and can even break, or be recalled.
Of course, I am not an engineer and this is my opinion.