Towing/backing a 5th is different but super easy to get the hang of. I've gone back and forth between the two a few times over the years and the learning curve is quick.
The 5th is slower to react when back because the pivot point is right over the axle. The 5th will tend to track inside of where a TT would when driving forward so watch your turns and when in doubt go wide.
The height of the 5th is probably the biggest difference. Watch those gas station awnings and low hanging trees in the residential neighborhoods.