Well, it's almost here. We pick up our new fifth wheel this Saturday. I've never towed one before but I'm sure I'll pick it up. I've towed regular trailers for a long time. Think my only issue will be...
The tires on the 5er will track inside your truck tires. That is why you need to make wide turns. As for backing, when I made the switch from TT, I went to an empty parking lot and played a while. Then, since it was early in the season and our local Ohio state park wasn't open yet, I went to the state park campground, and backed into a bunch of sites. This was the best practice.
2x looking up. Know your height, and watch clearance signs.