Most tire issues still come down to weight.
If you are loading any tire at its weight limit, it will run hotter, wear faster and be more prone to failure.
We all know that many of the RV manufacturers put Axles and Tires that are marginal at best and look good in the brochures for dry weight, then when we add options like 2nd A/C, Larger Refig, Generator, Dual Pane Windows and such the actual weight goes up the carrying capacity goes down and the RV gets close to the Gross Weight Rating of the axles and tires.
When running a trailer or 5er with a loaded weight of less than 12,000 lb. axle weight with a "G" Rated tire, they should last forever if the trailer is balanced and there is not more than 3,000 lbs on each tire. When running axle weight above 12,000 or more than 3,000 lbs per tire, even the "G" rated tire is getting a workout, this is the reason many have moved up to a 17.5" tire.
If you look at the brochures and then go on the lot and look at the yellow label the manufactures are required to put on RVs today that show actual "As Built" weight, many of them do not have much carrying capacity left before hitting max weights.
If more RVers had their trailers weighted with all their stuff as they travel, they would be surprised.
Like the dealer telling the 1/2 Ton Truck owner, "You can Pull Anything in the Lot"
If you can pack it in the trailer and still get the door closed, it must be Ok !!!!
We actually have 7,000 lb. axles but the manufacturer de-rated the axle weight rating to 6,800 lbs. since they put "E" Rated 3,400 lb. tires on the axle.