We have a 35' 5er. Works fine on my F350 SRW. But much larger/heavier I would want a dually.
Private RV parks you will likely never have a problem.
National/state/city/COE parks you MIGHT have a problem with the longer trailers. We have not had a problem yet, but have been in some parks where we could not have fit into many of the sites. Fortunately we have always been able to find one large enough, mainly because we do not go to them on busy travel times. But the larger sites tend to go first and a late comer with a long trailer could easily be out of luck.