I have found with my TST that I set the pressure about 2 psi above my target pressure before I install the TST sensor and most of the time the TST will report my target pressure.
What I consider most important is to get the tires on any axle as close to each other as possible. Then when on the road for more than 25 miles the pressures on any axle should be within a couple psi. If they are not time to determine why.
One time I found a tire that was about 4 psi lower than the other 3 on my trailer. Stopped at the next service area and this is what I found. A 3/8 by 2 inch bolt.
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The TPMS saved me from having a bad tire day.