First off, check the PSI/load rating for your wheels before you so putting on higher-rated tires. Even with a D tire, you may find that the wheels are only rated for a C pressure/load. Personally, I think an E tire on your rig is =way= overkill and a D will likely serve you well. If you =do= go with an E, there's certainly no need to put 80 psi rated wheels on, as you're likely never going to want to exceed 65 psi on those tires anyway. Also, given GY's recent track record on trailer tires (excepting the G-rated stuff), I'd not be in a rush to jump on the Endurance band wagon without a lot more miles and reports on them from those who are using them. Carlisle had a bad rep for years, but the last few years have really upgraded their tires and I'd put another set on my FW without hesitation. I'm running the older RH E's and have had zero problems with them. I do run at 80 psi though I'm placarded for D tires, unless I'm running light, then I'll drop to 70. Just my $0.02...
Lyle