although I don't store clothes long term in my RV like OP, I do store clothes long term in my S&B here in the humid, hot, more humid deep South. I have found the actual bags marked "Space Bags" or "original Space Bags" do seal and stay sealed pretty well. I have had clothes and linens in the bags stored in the attic and in closets that aren't frequently accessed and have had no issues with smells from them. If I put in garbage bag or just plastic tote, they seem to have a musty smell. the space bags are worth the cost, and do reduce volume too.