It seems counter intuitive, but C's are generally equipped for families with sleeping quarters for more than two for extended travel and A's are generally most comfortable for two people for extended travel.
WE have driven to and from Alaska only one time going up the Klondike Loop and over Top of the World Highway to Taylor highway into Tok and back the other way :) with a stop in Haines and ferry to Skagway then down to Atlin for a side trip. This was all in a 36 foot 2 slide gasser towing a RAV4. The high vantage point and the broad windshield offer a great view and a lot of comfort. We never felt cramped and we made most of our stops in AK and YT on the side of the road or just off. The tank capacity for freshwater and sewage was very important as there are just not a lot places to dump and fill and there can be a charge for every time you need to dump (they do not measure volume)
When I get into the driving compartment of a C, I feel cramped and I don;t like that so much of the coach body extends well out to the side from where I am sitting. In the end this is all very personal and we each either like what we have or are looking to change.