Enterprise is by far the most non-airport available agency. Best bet is to use their web site to see if there is one near where you want to set up camp. Then call and ask about pick up. With a little advance notice they will pick you up and they will have a car. In ten years we have never had a problem. And no, we do not work for Enterprise. One point. Airport agencies almost never will pick you up.
That being said, when we retire next year we will likely start towing. Rental has worked for vacations and weekends.
As for rental price - we just rented a Ford Focus on the Outer Banks for $175 for 7 days. I also have a reservation for a three day weekend at $9.99/day. They always nail you when you rent for a period if time other than by the week, month, or weekend.