Can it be done? -- Yes
Do you need chains? -- Maybe, depending on snow depth or required in a snow area. If yes,on which tires? -- Outer duals minimally
Have YOU done it before? -- Yes, once when I couldn't avoid it.
Would you be better off with a certain type of tire? Snow tire for a motor Home? -- Chains or normal tires; I wouldn't bother with snow tires.
Does the heavy weight of the motor home help or hurt? I don't think it matters.
Could I still tow my car? -- I've never tried.
Lastly, I don't recommend doing it at all.
