I would never go as far up I-95 as DC....1st problem is construction day and night starting below Quantico, VA. I travel this often and it sucks. Hit I-26 in SC and take it to I-77 up to I-81 in Virginia. At Scranton, PA jog a little South on I-380 and then pick up I-84 East (North?)Part of this is Mass Tpk. to I-90 to I-495 to exit 30 Littleton......You won't be sorry as you miss all of the BIG city hassles and most of the tolls other than Mass Tpk. Be aware of the weather in the winter but Interstates are usually open even in the worst conditions. I have made the trip both ways, I-95, and it might be longer in miles but its shorter in time and agreivation.