Hopefully the cooling system was previously flushed completely. If not, you might be suffering Death by Dex-Cool. Once it ages out (10 years) or gets exposed to oxygen from a leak, it'll start to coagulate, and the pH drops which starts corroding things.
The good news is that it hasn't completely overheated, so doing a full-flush now should get all the old stuff out, and adding a chemical flush will remove any of the "Tapioca" that forms when it starts breaking down.
Do beware that the first generation 6.0 in the Chevy chassis only had a 16,000 GCWR, same as the vans. When Workhorse came out with their version of the 4500 chassis, with the workhorse badge, they bumped it up to 17,600 pounds. Workhorse did some engineering to upgrade components for the upgraded GVWR, but I don't know if anything was changed in the cooling system to allow for the higher GCWR. The 20,000 GCWR did not come out until the 6L80/85e was introduced.
IAMICHABOD - Do you happen to have the full list of upgrades Workhorse did? If they upgraded any of the cooling, it would be easy to add those items. And if they didn't do anything, I think you can assume the Workhorse GCWR as-is.