Is there a preferred oil for the Ford V10 E-450?

"Is there a preferred oil for the Ford V10 E-450?"

Well, I guess the real question here is, "Preferred by Who?" If you want to listen to the engineers who designed and built your engine, and millions of others just like it, go with what your owners manual says. Plturne has figured that out. (see link above) If you prefer not to, go with everyone (anyone) else. As long as the oil you choose meets/exceeds the required specifications, . . . your good to go. It's that simple.

Chum lee