The approach of leaving a rear vent open to help suck cool cab air throughout the motorhome would be unacceptable to us: We travel with all vents and windows closed and the cab A/C on "MAX AIR" so that the A/C doesn't bring outside air in - it only continuously recirculates air inside the motorhome.
The cab air conditioning is a lot more efficient at cooling this way (because the cab A/C is no longer having to continuously cool hot new outside air). But here's the big reason for why we do it this way - you don't get outside air continuously flowing through the motorhome from the front air intake (usually somewhere around the front fenders) and then on back to exit through an open vent in the rear ... WHICH MEANS ... the inside of the motorhome stays a lot more free of dust and dirt that otherwise would be carried in from the outside air. This also helps make the more efficient cab A/C cool the entire coach area even better. We use the same approach in our car to help keep it's interior cleaner longer.
On RV trips we also stop to shop, eat lunch, and dry camp off and on - so of course we're very generous about using the generator and rooftop AC to keep the interior of the motorhome cool as required when we're not traveling. We have even run both the rooftop air and idle the V10 for cab air when parked for a fast lunch cool-down if we have been out and about away from the motorhome walking or hiking in scorching temperatures.