I check my tire pressures at the beginning of any travel day. I also check it frequently while traveling, but I have TST TPMS. Once settled, I turn it off. I run my tire pressure according to axle weight plus 5. 110/Front 100/Drive 90/tag. Tires wear evenly and coach rides smoothly. Even with changes in altitude I'm still within chart specs. From Yuma @ 117 to Amarillo @ 65 degrees they're still within specs. I only rarely add or subtract pressure in our travels....Just my experience....I could open another can of worms and talk about tire temperatures, but that's another post.....Dennis