The big downside to class A & Cs are mechanical issues. If something breaks you lose both your house and your car. Of course most people tow a toad.
The nice thing about them is one button and your camping or driving. I very nice luxury.
5vers and TT are nice since the TV (tow vehicle) and the trailer are separate. I had a problem with the TV once, and we settled into a Walmart parking lot while I got the diesel serviced. Likewise if the trailer has a problem, you have the TV.
Of course, you could have what happened to me in Florida. The person who hit me wasn't satisfied with just taking out my trailer, they ripped off their left front wheel and bent the right front wheel assembly on my TV.
Foreign travel.
Just remember when you leave the US you are subject to the host nation's laws. Not all laws you are familiar with are the same across the border. If your plan is drive south be aware of all the laws especially where your pets are concerned--both ways.
You also do need to be concerned with crime and political strife. Traveling in groups, especially with people experienced in travel south of the border is an excellent idea.
I sure it would be exciting to go to some of the off the beaten path places. Mexico is rich with history. Exciting as it is, do your homework and avoid being a story on the national news channels.