My parents had a class C and I drove it on their last long trip before they sold it. I found the overhang distracting when driving and the cab area wasn't really part of the living quarters while stopped. Every class C they owned had different levels in the floor, which made moving around tricky.
I knew I wanted a MH, and ended up buying a Class A. It is actually easier to drive than the Class C. Different but easier. I sit up high enough I can see easily whether it is looking up for overhead obstructions, looking down the road or looking before pulling out at an intersection. My floor is level, which is a real bonus for my knees and my lack of coordination (I have been known to trip over a shadow).
Now I will say, I bought MH to eventually fulltime in. If I were just going for weekends, the Class C might fit my needs (and budget), but since I wanted something to be able to full time I knew the Class A was for me.