Our 24' C (see sig), fits our use perfectly, just my bride and I and da pooch. No need for a Toad as the rig fits anywhere we need to go(though our V-10 E-350 is rated to tow 5,000#). Ours is a so called "wide body" at 101" and with 7' of headroom throughout the coach it is roomier than a lot of longer C's(without the extra overhang and no need for a slide).
The handling/parking is a piece of cake and it goes down any road or into any site without complaint. I think 24' is the threshold for a number of factors. Anything larger and I would probably want the E-450 chassis but 24' and less the E-350, with its better mileage and smoother ride, is the way to go.
As always.... Opinions and YMMV.
:C