Atlantic Coastal drive from Jacksonville to New York

I've done some of this route in our RV and on a MC.

Try Route 25 North from Brunswick, then Route 17 North to Charleston and beyond. If the weather is good, take the ferry in NC and visit the barrier islands (Ocracoke, Nags Head...etc) which is Rt12. Then across the Chesapeake Bay on RT13 and hit the Delmarva area to the Cape May ferry...then your on your own! RT301 is also a nice option in many stretches.