DrumZ,
You've drawn responses from some of our most thoughtful members. Adding my $.02, their idea of checking Weight, Weight Distribution, and Tire Pressures, will cost you about $10 (truck stop CAT Scale) and provide info that's essential even if you take additional measures. If you tow a vehicle or trailer, tow it with you to the scales and you'll get a separate weight for it. Again, useful. Go to the scales loaded with People, LPG, Water, and all at Stuff you take on a trip. Bring a
Load to Inflation Chart and then adjust pressure right there at the service plaza. You can use Michelin's chart for any brand of tire as long as the detail numbers match. You probably have second one on the page LT225/75R16E. Just notice Front and Rear (called Single and Dual) are different, and the weights are for one Corner of the RV. Double the charted values to match the scale weights.
If you don't find at least 75-pct or so of front axle capacity in actual front axle weight, or alternatively, at least 1/3 to 40-pct of total weight on the front axle, try to shift weight by moving it forward or at least removing it from aft of the rear axle. Water and waste tanks make a big difference if you run with them full.
From there, there's Alignment. E-Series Caster and Camber are set by switching different Upper Ball Joint Bushings. Then the Toe is set. ALL TOO MANY shops set the Toe on Ford Vans and Chassis, collect their bill, and call it good. NOT SO! You need that Caster and Camber set, and set to specs proven good for RV's. Particularly the CASTER. Shops want to set to mid-range of +3* and a Class C needs +5* or more Left, and +5.5* Right, to track well. Left Camber +1/4*, Right Camber 0*, and Toe slightly IN, like 1/8" to no more than 1/4". I'm told installing a Safe-T-Plus steering centering/stabilizing device in place of the OEM shock absorber on the steering linkage, will accomplish about the same as adjusting Caster.
I didn't catch the Model Year of your Chassis, but an E350 may not have a rear sway bar. If it doesn't, Hellwig sells a kit to add one. Many of their kits replace one that's already there. The one you're looking for has brackets with clamps that look like muffler clamps. A rear sway bar, or a bigger replacement for an OEM one, WILL help with tracking and handling.
So will an upgraded Front Sway Bar. So will a Rear Track Bar, but I'm trying to list the big hitters first:
Weight, Tire Pressure, Loading
Alignment
Add/Upgrade Rear Sway Bar
Then, perhaps, Front Sway Bar, Safe-T-Plus (Class C uses 31-140 plus a bracket kit), Rear Track Bar