Hi Suprz,
When buying an RV most people do not take a looooong test drive. I know we didn't. So often you get stuck with what it is. Some MH vendor units (on Ford Chassis) seem to drive better than others...luck of the draw? There are things you can do to make them handle better but some are ok with just making sure the alignment is correct. We were very lucky. Purchased a used Winnebago B+ and it handles fine for a large vehicle. No improvements required.
We typically drive long days. Stop every 2+ hours for a break. But (my opinion) you will be tired after 10 to 12 hours behind the wheel. I have driven ours 700+ miles and I was really tired at the end of the day. Left at 4:00am and stopped for the night at 7:00pm. It was a long day and its a large vehicle...lots of things to pay attention to when you are on the road.
However, I love to drive our motorhome. Just a cool way to travel. Never get to spend as much time as I would like traveling that way. So if you have to drive long days in a motorhome....that is (to me) a neat part of the vacation. i.e. its not just the destination, but also about the journey getting there. Have lots of fun along the way ;-).