Ride quality of class C vs. pulling trailer with truck

My DW and I are contemplating moving to a Class C in a couple of years. We've been camping for many years and progressed through 3 popup campers, a 29' Sunline TT pulled by a 2001 Dodge dually (V-10 gasser) and our current rig (27' Winnebago pulled by a Tundra). My wife has experienced some back issues which has led to this question. Is the ride quality of a class C typically better than that of a pickup truck pulling a trailer.

Obviously, there are many variables involved i.e. type of hitch, weight of trailer, towing under/over capacity etc. I really don't want this thread to get bogged down with those discussions. I'm more interested in hearing from class C owners that previously towed travel trailers and their experiences.

And, most likely, we would be looking for a 30' or slightly larger class C which offers a walk around bed. At our age, we really don't want to be crawling over each other for the nightly visits to the bathroom!

Thanks in advance for your responces!