We exited via Tuolomne Meadows to 395 a couple of years ago in a 41 ft MH + toad. Post Yosemite the road is fine though steep. I definitely used and enjoyed the Jake brake.
The road in Yosemite is very narrow and has almost no shoulder in many places. I asked a ranger about it and he said that "mirrors slap all the time" between large vehicles traveling in opposite directions.
The trip was so convenient and unbelievably beautiful that I would do it again; however, I would try to travel that stretch when there was very little traffic. It was very busy when we traveled and it was nerve wracking.