If you have the schematic that shows which items are powered via that fuse
Remove fuse check continuity to ground from that feed to ground,
Now the slow part, one by one disconnect each item until you find the one that makes your continuity short disappear
I suspect that something has failed, something that would automatically have power, not something you are going to manually b operate a switch for,
Unless you have had a rodent chewing on wires, that should be visible unless it chewed a random spot In harness somewhere, creating a short between that hot feed and the ground lead for something else
How long as it been parked