You need to be able to use the bed with the slide in. Having to deploy the slide to use the bed is not generally an acceptable thing, as there are circumstances where you cannot or do not want to deploy the slide. Parked close to a tree, another camper (yes, they can be that close) or in a Wal-Mart parking lot, are all good reasons to keep the slide in.
In my opinion, slide deployment should never be a necessity to using the interior of the coach/trailer/whatever. It makes it nicer, but should not be mandatory for using it.
Charles