Mr Bojangles wrote:
Using a software package DeLorme Street Atlas (2013),
Planned trip using Rt #95 Miles are 1,274, and time is 22.3 Hrs.
Planned trip using Rt #81 Miles are 1,305, and time is 22.5 Hrs.
One avoids traffic and views through major Eastern cities using Rt #81, Rt# 77.
Just my thinking.
Hope it helps.
That's good thinking. 81 to 77 etc. is my route down.  
Not sure if it fits in your timeline for a stop, but Falling Waters Campsite in Falling Waters, WV is one of our stops along the way down.  Easy out if you leave early in the morning.  
Falling Waters Campsite reviews