They ride like log trucks on even small bumpiness etc.
Tires on our little black car are only 18 inch but with the suspension it is a firm ride. The bigger wheel weigh more. Some car's I've seen they had to lower the suspension and do wheel well work. They just about had to change rear differential gears too. It cost them mileage.
Those little rubber band tires run pretty high pressures for a car.
The twenties on the Edge are 45 lb. The 18's on the black car are at 38-40 with performance tires.
I saw a 70's Chevy the other day with rims that appeared to be in the neighborhood of thirty inches. They were certainly larger diameter than the MH or a Semi by a good bit. They would have to jump down from the car or maybe they had a rope ladder.