You will get all kinds of comments here, so I will start. I have driven our Ford V10 Triton over 80K miles so far, and have always used full synthetic oil, generally 5W20 Castrol. As far as the mileage goes, the oil weight is not going to make much difference. From what I hear and my experience, the Triton is a shorter-stroke engine, and revs higher than some others. I feel that the synthetic oil gives better protection for this engine, consitering that I sometimes need to run the higher revs for extended time, especially for long grades. I have been told by folks that know engines better than I do that the climbs do not hurt, just to try and keep it under 4000 rmp range but occasionally higher is OK. I understand that this engine develops max horsepower up in the 3500-4200 range. I feel better protected with the synthetic oil , and not having to worry about oil changes as often. This is all IMHO, and I will not get upset if anyone disputes me. I will just continue to do as I please, and let them do theirs.