The standard RV is a simple gravity system. The waste tank is directly below and when you push the pedal, a trap door opens and everything falls straight down (or pretty close to straight). Very simple and not much to fail. About the worst thing is the seal on the trap door can wear out.
Vac-u-flush is really a marine head (toilet). On boats it's actually rare to have the tank directly below the toilet and on sailboats, you could be at a 20-30degree heel. So an RV style toilet doesn't work. By using a pumping system, they can force the waste horizontally or even uphill.
In some RVs, it's not practical to place the waste tank directly under the toilet, so they use a marine head. Having had these on boats, I would not want one if there was any other option (in fact, we replaced the one on our boat with a composting head...a different subject all together). They tend to be smellier and are far more prone to failures (A leaky seal on an RV toilet and it's a nuisance but you can still use it until you get it fixed...If pump on a marine head goes out, you are done using it until you can get it repaired). Also, they tend to use much smaller 1.5" diameter flexible hoses which are prone to clogging and given a few years, odors start going right thru the hoses.
I wouldn't necessarily rule out an RV that has one but it's not a selling point.