My quick answer to the OP's opening question is "no". When it comes to a motor home towing something, I look at it the same as asking if a car I was thinking of buying typically had 1 or 4 occupants making the car work harder. I sort of think of it as a mute question.
At the same time I understand why the question is asked over excessive wear and tear on the chassis. I am sure there is something measurable, but negligible. In our case, wear and tear on the brakes is actually less than if we did not tow because our tow brake kit is setup so the brakes on our tow vehicle helps reduce braking distance than if we did not tow at all.
If the chassis was not maintained properly, maybe towing just might add negative influence, so the question is not so mute after-all.
