Molly's sock eating resulted in two vacation incidents, now that I recall.  The one was when she couldn't quite close the deal at the rest stop.  The other was when she spit up a sock that must have been in there for weeks.  GAck!  In the motel room.  
 
I will say that she'd had some symptoms.  Not a loss of appetite but her GI tract had seemed just a little off for some weeks.  Then suddenly, up it came and after that she was all better.  But it was very subtle... I wasn't sure that I wasn't imagining until she chucked up that sock. 
She was a perfect dog in every other way, but she would steal socks and pantyhose in a heartbeat and eat them whole.   Once that started I had to get really careful about where my socks were.  I had someone stay with me for a while that had an office job and we had to have a serious talk about pantyhose security measures.