I doubt very much there is a medical miracle that can save your Mandie at this point in her life so why let her suffer and endure this pain and suffering longer than necessary??
I know how hard it is to let a beloved family member go, both furry and flesh, as I've experienced both first hand, while holding their paw/hand and it's very hard on us of course, but when it finally ends, the pain and suffering of the loved one is gone and they are finally at peace...
I know this sounds very cruel and heartless from a complete stranger on the damn internet... But, I beg you to consider the quality of life for your loved one at this time...
For me, it's knowing that they are no longer in pain that lets me grieve for them in a better light and remember all the great times we had together when times were good and not witnessing them suffer any longer..
My thoughts and prayers go out to you and your family.
Mitch