I have been using Avira on several machines for a number of years. Works well and is free. Only pop up I ever get is to tell me it ran an update. You can schedule that to happen whenever you want. I do use Malwarebytes and Spybot Search and Destroy for the occasional malware scans. I also run CCleaner occasionally. It is not just a great registry cleaner but has other tools that are very handy such as a simple to use way to manage programs running at startup. The Drive Wiper is also easy to use and understand.
Way back when I used Norton however over time it became quite the resource hog. I understand they have addressed that to some degree but can't say for sure just how well it works now. AVG was my choice when I dumped Norton. It worked well but I was noticing over time it too was becoming a little heavy. Not as bad as Norton. I put Avast on couple of machines and it was ok. About the same time I put Avira on a couple of others and I liked it. Bitdefender does have high ratings and a free version. Kaspersky ranks well. While it is not free it can be had on sale very reasonably. I have never used Security Essentials mainly because it has always been at the lower end of the ratings and there are so many other free options.
I suggest trying out Bitdefender, AVG, and Avira which are all free. If you don't like one of them shop around for a sale and get Kaspersky. Additionally I would highly suggest installing Malwarebytes and CCleaner. These can be run on an as needed basis my suggestion for most people is weekly but monthly works for many.