The OTA coverage is from West Palm Beach (WPTV NBC 5, WPEC CBS 12, WPBF ABC 25, WFLX FOX 29, WTVX CW 34, & WXEL PBS 43).
WPBF ABC 25, WTVX CW 34, and an independent station have their transmitters close enough to Fort Pierce to come in, no matter which direction you point.
The other four major stations all have their transmitters in the same area in Palm Beach County, so if you aim the antenna to maximize their signals, you should be able to get all of the OTA networks.
When we stayed a little further south at Hobe Sound (Jonathan Dickinson State Park), we could get all of the OTA stations without even raising our Sensar antenna. (That was a good thing, because we COULDN'T raise our Sensar antenna at the time!)
Of course, the tradeoff against Comcast cable is whether you want the other satellite channels. If you have Dish or Direct, that's a moot point, unless it's rainy season!