I haven't ever rotated our TT tires but we get them balanced, our automobile tires do get rotated to keep wear even across all four tires. Wouldn't hurt anything if you wanted to do so, good time to inspect brakes and bearings. We put lots of miles on our rig yearly and occasionally travel above 65mph on the interstates, therefore we replace our TT tires every four years regardless of wear. The ST tires we have on now all have ratings above 65mph, we always set inflation to max psi as stated on sidewall.