You can get to Labrador from Quebec, cross Labrador, then take a ferry from Blanc Sablon, QC to Newfoundland. In my photo collection are pics of me going the opposite way.
My choice was to stop for the tours of hydro dams and related developments. Labrador City had a special day the day I happened to be there and aside from various races, the whole place was closed up. Also, I should mention that you can drive all the way across Labrador now and some is paved. & I still think the rver who emailed each and every municipality with a web page had a great trip. Always ask locals.
Then when you get to Newfoundland give yourself at least two weeks, better 4 to visit all around. Without a doubt it's changed since I moved across the Gulf in 2008.
Fish/seafood for eating natch. Larger centers for general shopping and gasoline. Check Public Utilities Board for gas prices, ie. costs less Deer Lake through Corner Brook than south around Stephenville. St. John's being the largest most dense population area has lowest gas prices.
Some absolute musts: L'Anse aux Meadows, Gros Morne both sides of Bonne Bay, Cape St. Mary's Bird Sanctuary, a selection of St. John's. Check what festivals are where. Play Tempting Providence @ Gros Morne Theatre festival in Cow Head. 'Tis local history.
:B
