I guess you've figured out that they are in the front cap area. The pin box mount is an opening into that area.
If you leave honey bearing comb in there, more bees are likely to take over after you have killed the existing hive. Plus, you might not want to spray insecticides into your living area. I would call a pro exterminator.
I also like to save a hive whenever possible, but unless you are willing to disassemble the front of your trailer, it isn't going to be possible. Then again, disassembly might still be necessary. The pro will advise you.