I've pulled my trailer in the snow before. We left for Florida on a Friday morning, it snowed 6" on Thursday night. I'll be darned if I was spending one more day in the cold and snow... put the truck in 4wd and pulled through about 40 miles of snow. Drive slow and be sensible. If it is actively snowing and heavy, I would just pull off for the day.
After it snows, they should clear the roads... at least major highways. They know how to clear snow out there, shouldn't take too long before the road is safe to pass.