My wife has been on Coumadin since 1971. She has 2 mechanical heart valves, 3 bypass, and a pacemaker. Cleveland Clinic recommends to not stop Coumadin if you have mechanical heart valves. They replace her pacemaker without protime adjustment. She has had teeth extracted with normal protime. You need to find medical personnel that know how to adjust to Coumadin. Without Coumadin, she would not survive. Her normal range is 2.5 to 3.5 while most of the others on this site will be 2.0 to 3.0. Yes, we can still travel with the Coumadin testing issues. She was qualified for home testing, but prefers the Coumadin clinics across the USA. She has an order, the testing lab faxes the results to the home Coumadin clinic. They call on the cell telephone with the new results and adjusted dosage if needed. We use hospital outpatient since they run the test in house. Some of the laboratory companies send the samples to a central process laboratory that delays your information for 24 hrs. Our insurance covers this testing 100% P.S. We have traveled in 48 states with the mechanical valves.