Depends......mainly on how you folks drive, where you drive, what you tow....etc
Diff ratios are about 10% apart and "at the same road speed...you will gain about 10% more power
If you go lower (higher numeric) you will gain that much more power going higher numeric....lose about 10% going higher (lower numeric)...
BUT...you might lose MPG when not towing...using it as a CAR...some times...while towing heavy...you might gain a bit more MPG...as the engine won't be working as hard
Also, depends on whether your engine has enough RPMs before red line is required to take advantage of this