Purge might be good as long as someone hasn't turned the valve handwheel or opened the spitter screw.
There is a one way built in check valve that doesn't allow propane to flow out unless it is depressed when the acme nut or POL fitting is screwed into the cylinder valve. It is also depressed when the tank is filled.
With the cylinder under vacuum the poppet could open drawing air into the cylinder if the handwheel is turned. Air can also enter the cylinder if the spitter screw is opened.
A propane supplier told me if the cylinder is more than 6 months old he purges them with propane vapor anyways.