Lot's of people associate cigarette smoking with lung disease. While this is true, nicotine causes other deadly diseases. Pancreatic, bladder, oral, esophageal cancers. Heart disease is a biggy, that many people don't think of as being caused by smoking. Nicotine is a powerful vaso-constrictor. It causes the coronary arteries to constrict. That will slow the blood flow, just as if you stepped on a garden hose. If you have atherosclerotic deposits,(very common with a Western Diet)there is more 'stuff' to block the artery. If the blood is stopped from getting to the heart-the tissue dies.
As an RN, and a cancer patient-if someone told me there would have been something that I could have done to prevent this disease- you better believe I would have done it. My cancer was caused by genetic factors, so other than choosing different parents.....
It's kind of a no-brainer to me. Take care of your body, you only get one.