I have had to change a couple tires by the side of the road, compliments of Carlisle China ST tires. :) I put my 10 ton bottle jack under the axle U-bolts, but not on the axle tubing itself.
Trying to jack the frame high enough to allow a person to remove the tire would require extensive frame support and a very high lift jack. And I wouldn't do it anyway for fear of putting excessive stress on a single point of the frame.
And yes, my manual says to never use a jack on the axle. IMO another CYA statement insisted upon by the lawyers.