I'd change it before the trip..
One side effect of the Direct Injected engine is that the oil can get contaminated with raw fuel.. Not a whole lot of course, but enough that you can smell gas in the oil..
Over time, this will reduce the viscosity of the oil, so getting it changed with fresh oil before it becomes an issue is the best course to take..
I've changed my oil in my Ecoboost a couple of times already.
Planning on doing it again next weekend. I've got about 4000 miles on this current oil change. The truck has 10,500 miles on it now.
I did the first change at around 2500 miles. The next change at around 6400 miles.
I feel it can't hurt and I know I won't go over 5000 miles between changes.
Just what works for me and I'm fine with it. :)
Good luck!
Mitch