IMHO the safety and capability while towing outweighs the comfort on the other end, but I do understand where you are coming from. You yourself stated the LC is not built for towing. That should answer your question right there. Two thoughts if you don't mind spending some extra money:
1. Can you do anything to the F350 in advance to make it a more comfortable ride? Shocks, springs, whatever.
2. Are there car rental agencies where you can rent a Jeep or other 4x4 in the areas where you will want one? This would require a little extra coordination and a few more bucks but is it worth investigating?
Safety first comfort later.