Polyvinyl Chloride has a single plus feature going for it and lots of minuses. PVC is hard to slice and hard to do everything else in including bending the wire. Neoprene (Hypalon) is hard to abrade as noted above but it slices easier than PVC. EDPN DLO wire (locomotive) is a bit stiffer than hypalon but resists sliced much better and abrasion much better.
Rope stranded silicone jacketed wire is truly "wet spaghetti" flexible but other than having a very high temperature tolerance the insulation is delicate and definitely not as tough as either hypalon or PVC. Teflon, kynar, and other aerospace jacketing is both tougher and stiffer than hypalon.