2006 F-250 Viberation????

I have rotated tires front to rear and side to side with no change.. This is a 4WD drive vehicle but hasn't been off road while I have had it.. Rims are clean on inside.. Since I am planning on a trip soon, and I have a service contract on vehicle, I took it to a local dealer today for assessment.. Findings: Ball joints are good.. U-joint seems fine..front wheel bearings feel ok.. but after a drive on the freeway, the shop service person did acknowledge the buzzing vibration at 45-60 mph on freeway..they suspect failing front wheel bearing but vibration analysis will hopefully locate the location / source of problem on Thursday.. thanks to all who have responded with excellent ideas.. I will update as soon as problem is fixed in case anyone else has this issue..

OP, how fast is the vibration? Like a buzzing vibration or slower and heavy? Also is it speed dependent, as in , does it change with speed or what gear your in? Can you hear any noises? Have you taken the vehicle off road recently? My work truck gets mud inside the rims constantly and I have to remove the tires to clean it out. If it's a very fast almost buzzy feeling it's probably a U joint, a slower heavier vibration is usually a tire out of balance, or mud packed inside the rim.

Maybe it is a rear tire. I believe all tires should be checked for balance in this situation.

That speed says tires to me, try rotating front to rear and see if things change. If they were balanced properly, you might want to just replace them.

Four wheel drive or two wheel drive? Any weird sounds or "feel" when turning real sharp in one direction or the other? You can't tell by "looks" when the ball joints go bad, but you can hear them, especially someone outside the truck, and when you hit big bumps at speed.

Possibly tire out of round or u-joint going bad?